A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type gene
Species Mus musculus
Tissue Embryonic Fibroblast
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description We further found that constitutive Nampt over-expression increases SIRT1 activity, increases the expression of antioxidant genes, superoxide dismutase 2 and catalase and promotes resistance against oxidative stress. These findings suggest that Nampt over-
Regulation Gene NA
Year 2017
Pubmed ID 29178516
Title Nitration-mediated deficiency of cystathionine B-synthase activity accelerates the progression of hyperhomocysteinemia.
Drug Nicotinamide phosphoribosyltransferase
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA