Details
| Name | SIRT3 |
| Type | gene |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | Protein sequence,western blot |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | The protective effects of CR on oxidative stress and damage are diminished in mice lacking SIRT3, a mitochondrial deacetylase. SIRT3 reduces cellular ROS levels dependent on superoxide dismutase 2 (SOD2), a major mitochondrial antioxidant enzyme. SIRT3 de |
| Regulation Gene | NA |
| Year | 2010 |
| Pubmed ID | 21109198 |
| Title | Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |