Details
| Name | SIRT7 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | ChIP,PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Here, we uncovered a pivotal role of sirtuin 7 (SIRT7), a mammalian Sir2 homolog, in guarding against rDNA instability and show that this function of SIRT7 protects against senescence in primary human cells. |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29728458 |
| Title | The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | blood |
| Variant | NA |
| High-throughput | NA |