A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name s-KL
Type gene
Species Mus musculus
Tissue brain
Experiment Method qPCR
Up/Down Down
Pro/Anti Anti
Funtion Description aKlotho is a gene regulator of aging, increasing life expectancy when overexpressed and accelerating the development of aging phenotypes when inhibited.In mice, expression levels of the secreted isoform Klotho (s-KL) are very high in the brain
Regulation Gene NA
Year 2018
Pubmed ID 29086766
Title Secreted aKlotho isoform protects against age-dependent memory deficits.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA