| Name |
Smurf2
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
human primary fibroblast cell lines BJ (from newborn foreskin),WS1 (from fetal skin),and WI38 (from fetal lung)
|
| Experiment Method |
Western blot
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Smurf2 is the first gene found to be both up-regulated by telomere attrition and sufficient to induce senescence.
|
| Regulation Gene |
NA
|
| Year |
2004
|
| Pubmed ID |
15574587
|
| Title |
Smurf2 up-regulation activates telomere-dependent senescence
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|