A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD
Type gene
Species Drosophila melanogaster
Tissue Drosophila strains
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description Catalase overexpression significantly increased resistance to hydrogen peroxide but had neutral or slightly negative effects on the mean life span. Cu/ZnSOD overexpression extended the mean life span up to 48%. Simultaneous overexpression of catalase with
Regulation Gene NA
Year 1999
Pubmed ID 9858546
Title FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA