A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD1
Type gene
Species Drosophila melanogaster
Tissue Drosophila strains
Experiment Method Immunoblot
Up/Down Up
Pro/Anti Anti
Funtion Description We show that overexpression of a single gene, SOD1, in a single cell type, the motorneuron, extends normal lifespan by up to 40% and rescues the lifespan of a short-lived Sod null mutant. Elevated resistance to oxidative stress suggests that the lifespan
Regulation Gene NA
Year 1998
Pubmed ID 9620775
Title Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA