A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD2
Type gene
Species Homo sapiens
Tissue ITSCs
Experiment Method Immunocytochemistry;Reverse transcription Polymerase Chain Reaction;SMART-Seq2;Real-time PCR;Immunocytochemical analyzes
Up/Down Up
Pro/Anti Anti
Funtion Description TNF-a-dependent NF-kB-p65 activation was accompanied by significant neuroprotection against oxidative stress-induced neuronal death, which was surprisingly higher in neurons from female donors. Accordingly, sex-specific neuroprotection of female neurons w
Regulation Gene NA
Year 2018
Pubmed ID 30375448
Title NF-kB p65 directs sex-specific neuroprotection in human neurons.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA