A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD2
Type gene
Species Mus musculus
Tissue liver tissues
Experiment Method Western Blotting
Up/Down Down
Pro/Anti Pro
Funtion Description Analysis of the ADP-stimulated (state III) respiration rates for the young and middle-aged Sod2tm1Cje (+/) mice revealed that they were substantially below those of age-matched controls. Moreover, in old control (+/+) mice the state III rates declined to
Regulation Gene NA
Year 2001
Pubmed ID 11226230
Title Increased mitochondrial oxidative stress in the Sod2 (+/) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA