A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD2
Type gene
Species Drosophila melanogaster
Tissue Drosophila strains
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description Here we report that ablation of mitochondrial SOD2 through expression of a GAL4-regulated, inverted-repeat Sod2 RNA-interference transgene in an otherwise normal animal causes increased endogenous oxidative stress, resulting in loss of essential enzymatic
Regulation Gene NA
Year 2002
Pubmed ID 12456885
Title RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA