A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD2
Type gene
Species Mus musculus
Tissue hippocampal neurons
Experiment Method Western blot analysis,other
Up/Down Up
Pro/Anti Anti
Funtion Description Superoxide has been shown to be critically involved in several pathological manifestations of aging animals. In contrast, superoxide also can act as a signaling molecule to modulate signal transduction cascades required for hippocampal synaptic plasticity
Regulation Gene NA
Year 2007
Pubmed ID 17129739
Title Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA