A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD2
Type gene
Species Mus musculus
Tissue NA
Experiment Method PCR,other
Up/Down NA
Pro/Anti Anti
Funtion Description The mitochondria of young, long-lived, Mclk1(+/-) mice are dysfunctional, exhibiting reduced energy metabolism and a substantial increase in oxidative stress.The partial loss of mitochondrial superoxide detoxification in Sod2+/ mutants enhances the protec
Regulation Gene NA
Year 2009
Pubmed ID 19478076
Title Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant 1
High-throughput NA