A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD2
Type gene
Species Mus musculus
Tissue NA
Experiment Method RT-PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description Sirtuin 3 (SIRT3) is a member of the sirtuin family of proteins that promote longevity in many organisms. Increased expression of SIRT3 has been linked to an extended life span in humans. Here, we have shown that Sirt3 protects the mouse heart by blocking
Regulation Gene NA
Year 2009
Pubmed ID 19652361
Title Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo4a-dependent antioxidant defense mechanisms in mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA