A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD2
Type gene
Species Mus musculus
Tissue fibroblasts,mesenchyme-derived cells of connective tissues
Experiment Method other
Up/Down Down
Pro/Anti Anti
Funtion Description The connective tissue-specific lack of superoxide anion detoxification in the mitochondria results in reduced lifespan and premature onset of aging-related phenotypes such as weight loss, skin atrophy, kyphosis (curvature of the spine), osteoporosis and m
Regulation Gene NA
Year 2011
Pubmed ID 21108731
Title Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA