A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name spindlin1
Type gene
Species Mus musculus
Tissue NA
Experiment Method Immunofluorescent staining,SA-B-gal staining,Western blot
Up/Down Up
Pro/Anti pro
Funtion Description Human SPINDLIN1 is localized to interphase nucleus and mitotic chromosomes, and its expression in HeLa cells is not regulated in a cell cycledependent manner. When SPINDLIN1 is stably overexpressed in HeLa cells, it results in multinucleation of cells, an
Regulation Gene NA
Year 2008
Pubmed ID 18201843
Title Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA