A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SSB2
Type gene
Species Saccharomyces cerevisiae
Tissue NA
Experiment Method Real-time PCR,HAC1 mRNA splicing assay
Up/Down down
Pro/Anti Anti
Funtion Description We demonstrate for the first time that SSB2 deficiency results in reduced resistance to TM, while overexpression of SSB2 increases resistance to TM in an IRE1-HAC1 pathway-dependent manner; these observations are related to changes in intracellular unfold
Regulation Gene NA
Year 2018
Pubmed ID 30382435
Title Yeast molecular chaperone gene SSB2 is involved in the endoplasmic reticulum stress response
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA