A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name AMP
Type gene
Species Drosophila melanogaster
Tissue NA
Experiment Method Microarray;RT-PCR
Up/Down Down
Pro/Anti Anti
Funtion Description The downregulation of AMP genes, itself, extended lifespan with increased stress resistance. Especially, fat body-specific downregulation of Imd AMP genes exhibited a longer lifespan with higher heat resistance. The fat body is known to function in metabo
Regulation Gene NA
Year 2018
Pubmed ID 29677000
Title Stress resistance and lifespan enhanced by downregulation of antimicrobial peptide genes in the Imd pathway
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA