A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name STAG2
Type gene
Species Homo sapiens
Tissue VM-CUB-3,SK-ES-1,SK-NEP-1,TC-32,H4 etc.
Experiment Method Chromosome specific FISH;Chromosome orientation FISH (CO-FISH);Immunoblot analysis;Immunoprecipitation;Indirect immunofluorescence;C-circle assay;TRAP assay;SA B-galactosidase assay
Up/Down Down
Pro/Anti Anti
Funtion Description Loss of tumor suppressor STAG2 promotes telomere recombination and extends the replicative lifespan of normal human cells,our findings suggest that extending the lifespan of normal human cells due to inactivation of STAG2 could promote tumorigenesis by ex
Regulation Gene NA
Year 2017
Pubmed ID 28819029
Title Loss of tumor suppressor STAG2 promotes telomere recombination and extends the replicative lifespan of normal human cells
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA