A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name STAT3
Type gene
Species Homo sapiens
Tissue lung fibroblasts
Experiment Method PCR
Up/Down Up
Pro/Anti PRO
Funtion Description Exposing human lung fibroblasts to 150M hydrogen peroxide (H2O2) resulted in increased senescence-associated-B-galactosidase (SA-B-Gal) content, expression of p21 and interleukin (IL)-6, all of which are features of senescence. The shift into senescence w
Regulation Gene NA
Year 2019
Pubmed ID 30608861
Title STAT3 Regulates the Onset of Oxidant-Induced Senescence in Lung Fibroblasts.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA