Details
| Name | AOR |
| Type | gene |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | RT-PCR,ChIP,Western blot |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Bmi1 expression progressively declines in the neurons of aging mouse and human brains. In old brains, p53 accumulates at the promoter of AOR genes, correlating with a repressed chromatin state, down-regulation of AOR genes, and increased oxidative damages |
| Regulation Gene | NA |
| Year | 2012 |
| Pubmed ID | 22384090 |
| Title | Bmi6 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |