A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name STUB1
Type gene
Species Mus musculus
Tissue MEFs
Experiment Method Dot blot,other
Up/Down Down
Pro/Anti Pro
Funtion Description CHIP(STUB1) deficiency in mice leads to a markedly reduced life span, along with accelerated age-related pathophysiological phenotypes. These features were accompanied by indications of accelerated cellular senescence and increased indices of oxidative st
Regulation Gene NA
Year 2008
Pubmed ID 18411298
Title CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA