Details
| Name | SUV39H1 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | ESC,MSC |
| Experiment Method | RT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Werner syndrome (WS) is a premature aging disorder caused by WRN protein deficiency. Here, we report on the generation of a human WS model in human embryonic stem cells (ESCs). Differentiation of WRN-null ESCs to mesenchymal stem cells (MSCs) recapitulate |
| Regulation Gene | NA |
| Year | 2015 |
| Pubmed ID | 25931448 |
| Title | Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |