Details
| Name | TDP-43 |
| Type | gene |
| Species | Mus musculus |
| Tissue | never |
| Experiment Method | PCR,other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | TDP-43 encodes TDP-43 which is an RNA-binding protein important for many aspects of RNA metabolism. Abnormal accumulation of TDP-43 in the cytoplasm of affected neurons is a pathological hallmark of the neurodegenerative diseases frontotemporal dementia |
| Regulation Gene | NA |
| Year | 2017 |
| Pubmed ID | 29097807 |
| Title | TDP-43 accelerates age-dependent degeneration of interneurons. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |