| Name |
TERT
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
C33A, ME180, HeLa, and SiHa cells
|
| Experiment Method |
Luciferase assay;qPCR
|
| Up/Down |
Up
|
| Pro/Anti |
Anti
|
| Funtion Description |
Transient expression assays revealed that transcription of hTERT was significantly activated in cancer cell lines but repressed in normal primary cells. Using the fibroblast lineage at various stages of transformation, we found that transcription occurred
|
| Regulation Gene |
NA
|
| Year |
1999
|
| Pubmed ID |
9973199
|
| Title |
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|