A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TERT
Type gene
Species Mus musculus
Tissue NA
Experiment Method RT-PCR, Southern Blot,Western Blot
Up/Down Up
Pro/Anti Anti
Funtion Description Reseachers engineered a knock-in allele encoding a 4-hydroxytamoxifen (4-OHT)-inducible telomerase reverse transcriptase-oestrogen receptor (TERT-ER) under transcriptional control of the endogenous TERT promoter. Homozygous TERT-ER mice have short dysfunc
Regulation Gene NA
Year 2011
Pubmed ID 21113150
Title Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA