| Name |
TERT
|
| Type |
gene
|
| Species |
zebrafish
|
| Tissue |
NA
|
| Experiment Method |
PCR,Southern blot,Immunofluorescence,Immuno-FISH,Immunoblot
|
| Up/Down |
Down
|
| Pro/Anti |
Anti
|
| Funtion Description |
The first-generation tert(-/-) zebrafish die prematurely with shorter telomeres. tert(-/-) fish develop degenerative phenotypes, including premature infertility, gastrointestinal atrophy, and sarcopaenia. tert(-/-) mutants have impaired cell proliferation
|
| Regulation Gene |
NA
|
| Year |
2013
|
| Pubmed ID |
23349637
|
| Title |
Telomerase is required for zebrafish lifespan.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|