A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TET2
Type gene
Species Homo sapiens
Tissue Blood cells
Experiment Method genetargeted deep sequencing
Up/Down NA
Pro/Anti NA
Funtion Description We report a higher overall prevalence of driver mutations (13.7%), which occurred mostly (93%) in DNMT3A or TET2 and were highly age-correlated.
Regulation Gene NA
Year 2017
Pubmed ID 28655780
Title DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutations
High-throughput NA