| Name |
TGF-B
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
human corneal endothelial cell B4G12
|
| Experiment Method |
Quantitative RT-PCR ;Western blot
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
transforming growth factor-B (TGF-B) is elevated in the CE of late graft failure. In addition, senescence-associated gene p21 and p16 are increased as well, which is consistent with their elevation upon TGF-B treatment in human corneal endothelial cell B4
|
| Regulation Gene |
NA
|
| Year |
2018
|
| Pubmed ID |
30482886
|
| Title |
TGF-B induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|