A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TGF-B1
Type gene
Species Homo sapiens
Tissue muscle
Experiment Method qPCR;Western blotting
Up/Down Up
Pro/Anti Pro
Funtion Description Expression of mRNA encoding the pro-fibrotic factors; axin 2, collagen III, B-catenin and fibronectin, were all significantly higher (all p<0.05) in the older participants (350, 170, 298, and 641%, respectively). Furthermore, axin 2 and B-catenin mRNA wer
Regulation Gene NA
Year 2017
Pubmed ID 28493029
Title Age and sex differences in human skeletal muscle fibrosis markers and transforming growth factor-B signaling.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA