A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TNFA
Type gene
Species Homo sapiens
Tissue blood samples
Experiment Method Genotyping Assay
Up/Down Up
Pro/Anti Pro
Funtion Description Tumor necrosis factor alpha polymorphisms are associated with Parkinson's disease age at onset.Gender and ancestry did not differ between groups. High TNFA expression may contribute for faster dopaminergic neuron degeneration. In this context, a higher ge
Regulation Gene NA
Year 2017
Pubmed ID 28844731
Title Tumor necrosis factor alpha polymorphisms are associated with Parkinson's disease age at onset.
Drug NA
Disease Parkinson's disease
Environment Factors NA
Circulating 1
Variant rs1799964, rs18NANA63NA, rs1799724, rs18NANA629, rs361525
High-throughput NA