i) The drug-protein interaction network
ii) The table result of interaction with ORC6_Q9Y5N6
| Protein | Type | Gene Name | Drug | Drug Source | R | FDR | Cancer | |
|---|---|---|---|---|---|---|---|---|
 |
ORC6_Q9Y5N6 | Canonical | ORC6 | vinblastine | GDSC1:1004 | -0.14 | 4.151e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | methotrexate | GDSC1:1008 | -0.175 | 8.597e-03 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | tretinoin | GDSC1:1009 | 0.139 | 4.339e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | AZD7762 | GDSC1:1022 | -0.169 | 1.182e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | lestaurtinib | GDSC1:1024 | -0.143 | 3.709e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | AZD8055 | GDSC1:1059 | -0.144 | 3.545e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | CYC-202 | GDSC1:110 | 0.145 | 3.432e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | serdemetan | GDSC1:1133 | 0.158 | 1.948e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | FK-866 | GDSC1:1248 | -0.151 | 2.584e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | camptothecin | GDSC1:1494 | -0.158 | 1.949e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | olaparib | GDSC1:1495 | 0.144 | 3.510e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | TAK-715 | GDSC1:221 | 0.146 | 3.216e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | tubastatin-A | GDSC1:265 | 0.137 | 4.704e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | Bayer IKKb inhibitor | GDSC1:290 | 0.139 | 4.348e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | CDK9 inhibitor | GDSC1:345 | 0.143 | 3.752e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | venetoclax | GDSC1:412 | -0.141 | 3.979e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | entinostat | GDSC1:88 | -0.147 | 3.058e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | camptothecin | GDSC2:1003 | -0.194 | 3.195e-03 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | cisplatin | GDSC2:1005 | 0.147 | 3.122e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | cytarabine | GDSC2:1006 | -0.212 | 1.136e-03 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | AZD7762 | GDSC2:1022 | -0.201 | 2.198e-03 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | 5-fluorouracil | GDSC2:1073 | 0.173 | 9.515e-03 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | irinotecan | GDSC2:1088 | 0.149 | 2.885e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | oxaliplatin | GDSC2:1089 | 0.142 | 3.911e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | APR-246 | GDSC2:1131 | 0.144 | 3.590e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | dinaciclib | GDSC2:1180 | -0.135 | 4.974e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | gemcitabine | GDSC2:1190 | -0.137 | 4.624e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | epirubicin | GDSC2:1511 | -0.135 | 4.996e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | leflunomide | GDSC2:1578 | 0.138 | 4.457e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | OTX015 | GDSC2:1626 | -0.149 | 2.842e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | PRT062607 | GDSC2:1631 | 0.141 | 3.933e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | AGI-6780 | GDSC2:1634 | 0.136 | 4.806e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | oxaliplatin | GDSC2:1806 | 0.177 | 7.989e-03 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | dactinomycin | GDSC2:1811 | -0.141 | 3.953e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | fludarabine | GDSC2:1813 | 0.15 | 2.750e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | Podophyllotoxin bromide | GDSC2:1825 | -0.144 | 3.538e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | BI-97C1 | GDSC2:1849 | -0.153 | 2.391e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | GTPL8020 | GDSC2:1855 | 0.176 | 8.229e-03 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | BVD-523 | GDSC2:1908 | 0.154 | 2.290e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | venetoclax | GDSC2:1909 | -0.202 | 1.999e-03 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | ABT737 | GDSC2:1910 | -0.145 | 3.411e-02 | ALL |
|
ORC6_Q9Y5N6 | Canonical | ORC6 | VE 821 | GDSC2:2111 | 0.142 | 3.883e-02 | ALL |
