i) The drug-protein interaction network
ii) The table result of interaction with TM9SF3_Q9HD45
| Protein | Type | Gene Name | Drug | Drug Source | R | FDR | Cancer | |
|---|---|---|---|---|---|---|---|---|
 |
TM9SF3_Q9HD45 | Canonical | TM9SF3 | 5-fluorouracil | GDSC2:1073 | -0.15 | 2.770e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | 9-??-D-Arabinofuranosyl guanine | GDSC1:427 | -0.155 | 2.172e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | afatinib | GDSC1:1032 | -0.168 | 1.240e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | afatinib | GDSC2:1032 | -0.204 | 1.835e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | alisertib | GDSC1:431 | 0.182 | 5.951e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | amuvatinib | GDSC1:293 | -0.159 | 1.894e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | APR-246 | GDSC2:1131 | -0.148 | 3.050e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | AR-42 | GDSC1:272 | 0.148 | 2.983e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | ARRY-520 | GDSC1:474 | 0.229 | 3.937e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | AT7867 | GDSC1:356 | -0.175 | 8.508e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | AZD7762 | GDSC1:1022 | 0.182 | 6.019e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | AZD7762 | GDSC2:1022 | 0.149 | 2.930e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | Bayer IKKb inhibitor | GDSC1:290 | -0.225 | 5.058e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | BI-2536 | GDSC1:60 | 0.191 | 3.842e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | BIX 02189 | GDSC1:279 | -0.138 | 4.463e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | BMS-345541 | GDSC1:203 | -0.209 | 1.342e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | bortezomib | GDSC1:104 | 0.191 | 3.683e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | bortezomib | GDSC2:1191 | 0.14 | 4.185e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | cabozantinib | GDSC1:249 | -0.181 | 6.559e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | camptothecin | GDSC1:1494 | 0.205 | 1.749e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | camptothecin | GDSC2:1003 | 0.188 | 4.507e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | CAY10603 | GDSC1:276 | 0.152 | 2.533e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | CD532 | GDSC1:449 | 0.175 | 8.872e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | CGP-60474 | GDSC1:53 | 0.158 | 1.980e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | CHIR-99021 | GDSC1:1241 | -0.138 | 4.462e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | CINK4 | GDSC1:54 | -0.214 | 9.765e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | cisplatin | GDSC2:1005 | -0.145 | 3.403e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | CP-724714 | GDSC1:255 | -0.164 | 1.456e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | docetaxel | GDSC2:1007 | 0.181 | 6.370e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | Flavopiridol | GDSC1:432 | 0.223 | 5.729e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | foretinib | GDSC1:308 | 0.149 | 2.837e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | GDC-0941 | GDSC1:1058 | 0.138 | 4.433e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | GDC-0941 | GDSC1:1527 | 0.166 | 1.341e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | GDC0980 | GDSC1:382 | 0.178 | 7.310e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | gemcitabine | GDSC2:1190 | 0.158 | 1.942e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | GSK-2126458 | GDSC1:283 | 0.204 | 1.830e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | GW-843682X | GDSC1:87 | 0.194 | 3.256e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | I-BET-762 | GDSC2:1624 | -0.181 | 6.487e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | JQ1-(+) | + | 0.144 | 3.569e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | JW-7-52-1 | GDSC1:83 | 0.152 | 2.489e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | kb NB 142-70 | GDSC1:407 | -0.187 | 4.725e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | KIN001-139 | GDSC1:86 | 0.153 | 2.428e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | LDN-193189 | GDSC1:478 | 0.218 | 7.557e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | leflunomide | GDSC2:1578 | -0.16 | 1.779e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | lestaurtinib | GDSC1:1024 | 0.232 | 3.120e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | methotrexate | GDSC1:1008 | 0.196 | 2.863e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | MG-132 | GDSC1:9 | 0.162 | 1.650e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | mirin | GDSC1:1048 | -0.143 | 3.705e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | mirin | GDSC2:1048 | -0.14 | 4.076e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | navitoclax | GDSC1:1011 | 0.145 | 3.335e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | NSC 87877 | GDSC1:147 | 0.136 | 4.774e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | NSC319726 | GDSC1:461 | 0.172 | 9.963e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | NVP-BEZ235 | GDSC1:1057 | 0.18 | 6.600e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | olaparib | GDSC1:1495 | -0.169 | 1.137e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | OSI-930 | GDSC1:298 | -0.166 | 1.372e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | osimertinib | GDSC2:1919 | -0.142 | 3.879e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | oxaliplatin | GDSC2:1806 | -0.192 | 3.615e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | paclitaxel | GDSC1:11 | 0.183 | 5.674e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | parthenolide | GDSC1:89 | -0.186 | 4.953e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | PDK1 inhibitor 7 | GDSC1:287 | -0.196 | 2.897e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | pemetrexed | GDSC1:428 | 0.158 | 1.902e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | pevonedistat | GDSC1:1529 | 0.164 | 1.476e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | PFI-1 | GDSC1:1219 | -0.157 | 2.052e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | PI-103 | GDSC1:302 | 0.135 | 4.964e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | PIK-93 | GDSC1:303 | -0.146 | 3.218e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | pilaralisib | GDSC1:372 | -0.174 | 9.200e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | Podophyllotoxin bromide | GDSC2:1825 | 0.166 | 1.318e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | Pyridostatin | GDSC2:2044 | -0.158 | 1.898e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | QL-XI-92 | GDSC1:329 | -0.201 | 2.198e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | SB-715992 | GDSC1:208 | 0.186 | 4.855e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | SNX-2112 | GDSC1:328 | 0.171 | 1.069e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | sorafenib | GDSC2:1085 | -0.137 | 4.599e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | TAK-715 | GDSC1:221 | -0.208 | 1.466e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | temsirolimus | GDSC1:1016 | 0.156 | 2.149e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | THZ-2-102-1 | GDSC1:346 | 0.152 | 2.473e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | TL-1-85 | GDSC1:261 | -0.188 | 4.472e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | Torin 2 | GDSC1:371 | 0.171 | 1.066e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | tubastatin-A | GDSC1:265 | -0.243 | 1.476e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | venetoclax | GDSC1:412 | 0.158 | 1.901e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | vinblastine | GDSC1:1004 | 0.226 | 4.604e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | vinblastine | GDSC2:1004 | 0.201 | 2.194e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | vinorelbine | GDSC2:2048 | 0.155 | 2.252e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | voxtalisib | GDSC1:375 | -0.145 | 3.340e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | WYE-125132 | GDSC1:317 | 0.231 | 3.369e-04 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | WZ3105 | GDSC1:252 | 0.183 | 5.732e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | XMD13-2 | GDSC1:330 | -0.173 | 9.740e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | XMD14-99 | GDSC1:253 | -0.189 | 4.117e-03 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | Y-39983 | GDSC1:309 | -0.14 | 4.141e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | YK-4-279 | GDSC2:1239 | -0.157 | 2.061e-02 | ALL |
|
TM9SF3_Q9HD45 | Canonical | TM9SF3 | YM-155 | GDSC2:1941 | -0.182 | 5.966e-03 | ALL |
