Detail

Chr	chr9
start	21994778
end	22121097
lncRNA name	ANRIL
entrez id	100048912
hgnc id	HGNC:34341
ensg id	ENSG00000240498
refseq id	NR_003529
methods	qPCR etc.
regulated	up-regulated
function description	In a series of 12 breast tumor tissues showing a wide range of p14/ARF, p16/ CDKN2A, and p15/CDKN2B mRNA levels, we also observed a stronger positive correlation of ANRIL with p14/ARF than with p16/ CDKN2A or p15/CDKN2B. This study points to the existence of a new gene within the p15/CDKN2B-p16/CDKN2A-p14/ARF locus putatively involved in melanoma-NST syndrome families and in melanoma-prone families with no identified p16/CDKN2A mutations as well as in somatic tumors.
pubmed id	17440112
year	2007
title	Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF.
drug	X
circulating	X
survival	X