Detail

Chr	chr10
start	118046279
end	118210153
lncRNA name	CASC2
entrez id	255082
hgnc id	HGNC:22933
ensg id	ENSG00000177640
refseq id	NR_026939
methods	qPCR, Western blot, in vitro knockdown etc.
regulated	down-regulated
function description	Overexpression of lncRNA CASC2 significantly repressed proliferation and metastasis while caused cell cycle arrest and much more early apoptosis of breast cancer.The inactivation of TGF-signal pathway was involved in the function of lncRNA CASC2.lncRNA CASC2 was a key factor in the tumorigenesis and malignancy of breast cancer, thereby possibly was a potential therapy target for the treatment of breast cancer.
pubmed id	29523222
year	2018
title	Up-regulation of lncRNA CASC2 suppresses cell proliferation and metastasis of breast cancer via inactivating of the TGF-signaling pathway.
drug	X
circulating	X
survival	X