Detail

Chr	chr16
start	54845189
end	54929189
lncRNA name	CRNDE
entrez id	NA
hgnc id	NA
ensg id	ENSG00000245694
refseq id	NA
methods	qPCR
regulated	up-regulated
function description	CRNDE expression is remarkably up-regulated in BC tissue specimens and cell lines in comparison to corresponding normal tissues and normal human breast epithelial cells. Up-regulated CRNDE expression was greatly associated with larger tumor size, advanced TNM stage and unfavorable prognosis of BC patients. We uncovered that miR-136 is a bona fide binding target of CRNDE, and that up-regulation of CRNDE promoted the mRNA and protein expressions of B-catenin, c-myc and cyclinD1.
pubmed id	28469804
year	2017
title	Long noncoding RNA CRNDE activates Wnt/B-catenin signaling pathway through acting as a molecular sponge of microRNA-136 in human breast cancer
drug	X
circulating	X
survival	V