Detail

Chr	chr21
start	40383083
end	40385358
lncRNA name	DSCAM-AS1
entrez id	100506492
hgnc id	HGNC:40197
ensg id	ENSG00000235123
refseq id	NR_038896
methods	RNA-seq, qPCR, RNAi, ChIP, Cell proliferation assay etc.
regulated	up-regulated
function description	The most abundant AER-lncRNA, DSCAM-AS1, is expressed in ERa+ breast carcinoma, but not in pre-neoplastic lesions, and correlates inversely with EMT markers. Down-regulation of DSCAM-AS1 recapitulated, in part, the effect of silencing ERa, i.e. growth arrest and induction of EMT markers.
pubmed id	26621851
year	2016
title	Luminal long non-coding RNAs regulated by estrogen receptor alpha in a ligand-independent manner show functional roles in breast cancer.
drug	X
circulating	X
survival	X