The Genomic Atlas of Breast Cancer — the non-coding theme
| Chr | chr12 |
| start | 53962308 |
| end | 53974956 |
| lncRNA name | HOTAIR |
| entrez id | 100124700 |
| hgnc id | HGNC:33510 |
| ensg id | ENSG00000228630 |
| refseq id | NR_003716 |
| methods | qPCR, RNAi, Luciferase reporter assay |
| regulated | differential expression |
| function description | Treatment of mice harboring platinum-resistant ovarian tumor xenografts with pHLIP-PNA constructs suppressed HOTAIR activity, reduced tumor formation and improved survival. |
| pubmed id | 28420874 |
| year | 2017 |
| title | Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancer |
| drug | V |
| circulating | X |
| survival | V |
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