| Chr | chr21 |
| start | 34157724 |
| end | 34190244 |
| lncRNA name | LINC00310 |
| entrez id | 114036 |
| hgnc id | HGNC:16414 |
| ensg id | ENSG00000227456 |
| refseq id | NR_027266 |
| methods | qRT-PCR, Western blot analysis |
| regulated | up-regulated |
| function description | LINC00310 was increased as breast cancer progressed, and the deregulation of LINC00310 was significantly associated with patients' survival. LINC00310 promoted cell proliferation by regulating c-Myc expression in?vitro. LINC00310 KO significantly suppressed tumour growth in?vivo. serum LINC00310 expression was significantly up-regulated in patients with breast cancer, LINC00310 had a powerful capability of distinguishing patients with breast cancer from healthy individuals |
| pubmed id | 29993199 |
| year | 2018 |
| title | The oncogenic potentials and diagnostic significance of long non-coding RNALINC00310 in breast cancer. |
| drug | X |
| circulating | V |
| survival | V |
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