Detail

Chr	chr5
start	2712591
end	2715237
lncRNA name	LSINCT5
entrez id	101234261
hgnc id	HGNC:37824
ensg id	NA
refseq id	NR_145480
methods	qPCR, Northern blot etc.
regulated	up-regulated
function description	LSINCT5 is overexpressed in breast and ovarian cancer cell lines and tumor tissues, relative to their normal counterpart. In addition, knocking down the expression of LSINCT5 in cancer-derived cell lines causes a decrease in cellular proliferation. Two genes that were significantly downregulated were the lncRNA NEAT-1 and a protein coding gene PSPC1. We have therefore characterized a novel lncRNA that is overexpressed in breast and ovarian cancers, enhances cellular proliferation and may play a significant role in multiple processes.
pubmed id	21532345
year	2011
title	LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation.
drug	X
circulating	X
survival	X