Detail

Chr	chr7
start	79452877
end	79471208
lncRNA name	MAGI2-AS3
entrez id	100505881
hgnc id	HGNC:40862
ensg id	ENSG00000234456
refseq id	NR_038343
methods	qPCR, Western blot etc.
regulated	down-regulated
function description	Our results showed MAGI2-AS3 to be down-regulated in breast cancer tissues compared to normal adjacent tissues. Moreover, MAGI2-AS3 markedly inhibited breast cancer cell growth and increased expression of Fas and Fas ligand (FasL). In conclusion, our data suggest that MAGI2-AS3 expression is decreased in breast cancer and that MAGI2-AS3 plays an important role as a tumour suppressor by targeting Fas and FasL signalling.
pubmed id	29679339
year	2018
title	Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
drug	X
circulating	X
survival	X