Detail

Chr	chr11
start	65497688
end	65506516
lncRNA name	MALAT1
entrez id	378938
hgnc id	HGNC:29665
ensg id	ENSG00000251562
refseq id	NR_002819
methods	qPCR etc.
regulated	down-regulated
function description	We found that MALAT1 was downregulated in breast tumor cell lines and cancer tissue, and showed that knockdown of MALAT1 in breast cancer cell lines induced an epithelial-to-mesenchymal transition (EMT) program via phosphatidylinositide-3 kinase-AKT pathways. Furthermore, lower expression of MALAT1 in breast cancer patients was associated with shorter relapse-free survival
pubmed id	26191181
year	2015
title	Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer
drug	X
circulating	X
survival	V