Detail

Chr	chr11
start	65497688
end	65506516
lncRNA name	MALAT1
entrez id	378938
hgnc id	HGNC:29665
ensg id	ENSG00000251562
refseq id	NR_002819
methods	qPCR, RNAi, Western blot etc.
regulated	up-regulated
function description	KDM5B induces the expression of MALAT1 and its effector metastasis- associated genes in triple negative breast carcinoma cells. KDM5B interacts with MALAT1 to modulate its expression in triple negative breast carcinoma cells and consequently facilitate invasion and associated metastatic activities.
pubmed id	26917489
year	2016
title	Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448.
drug	X
circulating	X
survival	X