Detail

Chr	chr11
start	65497688
end	65506516
lncRNA name	MALAT1
entrez id	378938
hgnc id	HGNC:29665
ensg id	ENSG00000251562
refseq id	NR_002819
methods	qPCR, Western blot, Luciferase reporter assay, Immunofluorescent assay etc.
regulated	up-regulated
function description	In this study we identified long non-coding RNA (lncRNA) MALAT1 can function as a ceRNA of cell division cycle 42 (cdc42) 3'UTR in inducing migration and invasion of breast cancer cells via miR-1. We found that miR-1 bound both MALAT1 and cdc42 3'UTR directly. Further study showed that MALAT1 induced migration and invasion of breast cancer cells while reduced the level of cdc42.
pubmed id	26926567
year	2016
title	MALAT1 induced migration and invasion of human breast cancer cells by competitively binding miR-1 with cdc42
drug	X
circulating	X
survival	X