The Genomic Atlas of Breast Cancer — the non-coding theme
| Chr | chr15 |
| start | 24978583 |
| end | 25419462 |
| lncRNA name | SNHG14 |
| entrez id | 104472715 |
| hgnc id | HGNC:37462 |
| ensg id | ENSG00000224078 |
| refseq id | NR_146177 |
| methods | qRT-PCR ect. |
| regulated | up-regulated |
| function description | lncRNA?SNHG14 may promote the effect of trastuzumab by targeting the apoptosis regulator Bcl?2 (Bcl?2)/apoptosis regulator BAX (Bax) signaling pathway. Furthermore, the expression level of serum exosomal lncRNA?SNHG14 was upregulated in patients who exhibited resistance to trastuzumab, compared with patients exhibiting a response. |
| pubmed id | 30015837 |
| year | 2018 |
| title | Exosome-mediated transfer of lncRNA?SNHG14 promotes trastuzumab chemoresistance in breast cancer. |
| drug | X |
| circulating | X |
| survival | X |
CopyRight © University of Miami, USA; Harbin Medical University, China
