Detail

Chr	chr7
start	44983023
end	44986961
lncRNA name	SNHG15
entrez id	285958
hgnc id	HGNC:27797
ensg id	ENSG00000232956
refseq id	NR_003697
methods	RT-PC, Western blot, Luciferase reporter assay, in vitro knockdown
regulated	up-regulated
function description	SNHG15 downregulation suppressed cell migration and invasion in MCF-7 and BT-20 cells, and inhibited epithelial-mesenchymal transition (EMT).In mechanism, we found that SNHG15 acted as a competing endogenous RNA to sponge miR-211-3p,which was downregulated in breast cancers and inhibited cell proliferation and migration. Our results showed that there was a negative correlation between SNHG15 and miR-211-3p expression in breast cancer patients.
pubmed id	29217194
year	2017
title	Long noncoding RNA SNHG15 promotes human breast cancer proliferation, migration and invasion by sponging miR-211-3p.
drug	X
circulating	X
survival	V