Detail

Chr	chr3
start	180989762
end	181836880
lncRNA name	SOX2OT
entrez id	347689
hgnc id	HGNC:20209
ensg id	ENSG00000242808
refseq id	NR_004053
methods	qPCR, Western blot etc.
regulated	up-regulated
function description	The expression of SOX2 and SOX2OT is concordant in breast cancer, differentially expressed in estrogen receptor positive and negative breast cancer samples and that both are up-regulated in suspension culture conditions that favor growth of stem cell phenotypes. Importantly, ectopic expression of SOX2OT led to an almost 20-fold increase in SOX2 expression, together with a reduced proliferation and increased breast cancer cell anchorage-independent growth.
pubmed id	25006803
year	2014
title	Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer.
drug	X
circulating	X
survival	X