Detail

Chr	chr5
start	140537340
end	140558252
lncRNA name	SRA1
entrez id	NA
hgnc id	NA
ensg id	ENSG00000213523
refseq id	NA
methods	qPCR etc.
regulated	differential expression
function description	We recently reported a decreased estrogen receptor activity in breast cancer cells overexpressing SRAP, suggesting antagonist roles played by SRA1 RNA and SRAP. The primary genomic sequence in and around intron-1 is sufficient to lead to a differential splicing of this intron. We propose that alternative splicing of intron-1 is one mechanism used by breast cancer cells to regulate the balance between coding and functional noncoding SRA1 RNAs.
pubmed id	16848684
year	2006
title	Alternative splicing of the first intron of the steroid receptor RNA activator (SRA) participates in the generation of coding and noncoding RNA isoforms in breast cancer cell lines.
drug	X
circulating	X
survival	X