Detail

Chr	chr1
start	3735601
end	3747336
lncRNA name	TP73-AS1
entrez id	57212
hgnc id	HGNC:29052
ensg id	ENSG00000227372
refseq id	NR_033708
methods	qPCR, Western blot, Luciferase reporter assay, in vitro knockdown
regulated	down-regulated
function description	Taken together, we demonstrated a TP73-AS1/miR-200a/ZEB1 regulating loop in breast cancer cells, which promote cancer cell invasion and migration through regulating E-cadherin and Twist expression. Suppressing TP73-AS1 expression to rescue miR-200a expression, thus to inhibit ZEB1 and Twist expression and up-regulate E-cadherin might improve breast cancer cell invasion and migration.
pubmed id	28857253
year	2017
title	A TP73-AS1/miR-200a/ZEB1 regulating loop promotes breast cancer cell invasion and migration.
drug	X
circulating	X
survival	X