Detail

Chr	chr18
start	57054558
end	57072119
lncRNA name	linc-ROR
entrez id	100885779
hgnc id	HGNC:43773
ensg id	ENSG00000258609
refseq id	NR_048536
methods	microarray, qPCR, Western blot etc.
regulated	up-regulated
function description	lincRNA-RoR was significant upregulated in DCIS and IDC tumor tissues, showing the highest expression in invasive tumor tissues. Overexpression of the long non-coding RNA, lincRNA-RoR, functions as a competitive endogenous RNA sponge in TNBC. Interestingly, lincRNA-RoR is dramatically upregulated in TNBC and in metastatic disease and knockdown restores miR-145 expression.
pubmed id	25253741
year	2014
title	lincRNA-RoR and miR-145 Regulate Invasion in Triple-negative Breast Cancer via Targeting ARF6.
drug	X
circulating	X
survival	X