Detail

Chr	chr18
start	57054558
end	57072119
lncRNA name	linc-ROR
entrez id	100885779
hgnc id	HGNC:43773
ensg id	ENSG00000258609
refseq id	NR_048536
methods	qPCR, RNAi, Western blot, MTT assay etc.
regulated	up-regulated
function description	Expression level of linc-ROR messenger RNA (mRNA) in BC tissues was clearly higher than that in adjacent normal tissues, and significant difference was found between expression level of linc-ROR mRNA and lymph node metastasis. Compared with vector cell, overexpressed linc-ROR cell presented decreased sensibility of 5-FU and paclitaxel with decreased E-cadherin expression, increased Vimentin, N-cadherin expression, and invasion ability.
pubmed id	26883251
year	2016
title	Linc-ROR induces epithelial-mesenchymal transition and contributes to drug resistance and invasion of breast cancer cells.
drug	V
circulating	X
survival	X